POSTPARTUM INDIGESTION WITH REFERENCE TO HEPATIC INSUFFICIENCY AND ITS THERAPEUTIC MANAGEMENT IN BUFFALOES
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Date
2011-12
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SRI VENKATESWARA VETERINARY UNIVERSITY TIRUPATI - 517 502. (A.P.) INDIA
Abstract
ABSTRACT:
The present investigation on postparturient indigestion (PPI) with hepatic insufficiency was under taken to study the incidence, clinical and biochemical findings, therapeutic efficacy of certain drugs in the treatment of PPI in buffaloes associated with hepatic insufficiency. Out of 181 recently calved (zero to two months after calving) buffaloes with the history of reduced feed intake and decreased milk yield presented at Ambulatory clinic, Mylardevpally, Campus Veterinary Hospital, College of Veterinary Science, Rajendranagar and a few periurban dairy farms located in and around Rajendranagar, Hyderabad, 64 (35.36%) buffaloes were found suffering with PPI. On detailed clinical examination and urine analysis of cases of PPI, it was observed that 30 (46.87 %) buffaloes had hepatic insufficiency. PPI with hepatic insufficiency of 30 buffaloes were divided in to three groups II, III and IV for conducting therapeutic trails. Ten apparently healthy postparturient buffaloes (group I) were subjected to clinical observations and biochemical investigations, and they served as healthy control group. The most common and consistent symptom observed in buffaloes suffering with PPI associated with hepatic insufficiency was reduction in feed intake and decreased milk yield. Scanty dung was observed in few cases. There was no significant difference in the values of temperature, pulse and respiratory rate of PPI animals associated with hepatic insufficiency before and after treatment, which indicated that PPI associated with hepatic insufficiency had no significant effect on the above parameters. All the animals during the treatment regained the appetite and milk yield was increased. Ruminal motility was increased significantly (P<0.01). Urine analysis was normal in all the groups after the treatment. Buffaloes of group II were treated with inj. Intalyte 0.5 g/kg b.wt i/v for one day and inj. Tribivet 10 ml i/m for 5 days. The mean serum glucose, total protein and albumin levels were increased significantly (P<0.01). There was a significant (P<0.01) increase in milk yield, improvement in milk yield was 46% and recovery in days was 3.60 ± 0.16. Buffaloes of group III were treated with inj.Intalyte 0.5 g/kg b.wt i/v for one day and inj.Catosol 5 ml/100kg b.wt i/m for 5 days. The mean serum glucose, total protein and albumin levels were increased significantly (P<0.01). The mean serum AST and GGT levels were decreased significantly (P<0.01). There was a significant (P<0.01) increase in milk yield, improvement in milk yield was 55% and recovery in days was 2.50 ± 0.17. The comparative means of above parameters revealed that the treatment given to group III animals was more effective. Buffaloes of group IV were treated with inj. Intalyte 0.5 g/kg b.wt i/v for one day and inj. Toxol 10 ml i/m for 5 days. The mean serum glucose, total protein and albumin levels were increased significantly (P<0.01). There was a significant (P<0.01) increase in milk yield, improvement in milk yield was 38.28% and recovery in days was 4.70 ± 0.15. Therefore, it can be concluded that the combination of inj. Intalyte for one day and inj. Catosal given for 5 days found to be more effective in the treatment of PPI with hepatic insufficiency.
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