Haemato-biochemical and therapeutic studies on ancylostomosis in dogs
| dc.contributor.advisor | Gupta, M. P. | |
| dc.contributor.author | De, Subhra | |
| dc.date.accessioned | 2018-08-14T07:50:09Z | |
| dc.date.available | 2018-08-14T07:50:09Z | |
| dc.date.issued | 2016 | |
| dc.description.abstract | Ancylostomosis is an important wide spread highly pathogenic metazoan nematodal parasitic infection of dogs and related carnivores which is an important zoonoses as it causes cutaneous larva migrans in humans. During the present study coproscopic examination of 250 dogs done in the laboratory by flotation technique of dogs presented in the GADVASU Small Animal Clinic, Ludhiana, Punjab from March 2015 to February 2016 and revealed the prevalence of ancylostomosis to be 13.20 per cent. The eggs per gram (epg) of faeces ranged from 600-28,300 as conducted by Mc master counting technique. Micrometry revealed the mean size of eggs were, length- 65.75 µm and the breath- 43.22 µm, means the species prevalent here in ludhiana is Ancylostoma caninum. The monthly prevalence of ancylostomosis from March to February varied from 5.55 to 26.66 per cent. The highest prevalence in the month of October and lowest in March. The values of the prevalence were correlated with the meteorological data. Highest prevalence was at the mean temperature of 25.10c and humidity 68 per cent which was seen in the month of October. The season-wise highest prevalence was in the season of Autumn and the lowest prevalence was in the month of winter. The prevalence was higher in male (14.37%) dogs as compared to their female counterparts (10.84%). The breed wise highest prevalence was seen in Mongrel 19.23%, followed by German sheperd 13.79%, Pomeranian 13.33% Pug 8.33 and in other breeds 6.89 per cent. The prevalence was higher in 0-6 months old pups (28%) than adults. The main clinical signs recorded were reduced body weight, anaemia as recorded by slight pale to pale mucous membrane, anorexia, pica, black color soft faces, vomition and diarrhoea. Four groups were made from naturally infected dogs came to the small animal Veterinary Medicine Clinic, GADVASU, Ludhiana. Group I (Healthy control), Group II (Non-treated control), Group III (Treated with ivermectin) and Group IV (Treated with pyrantel pamoate) were made. Group I, Group III, Group IV were consisted of 10 animals each and Group II consisted of 6 animals. The blood sample collected for Hemato-biochemical study on 0, 7th and 15th day. The study revealed decrease in Hb, PCV, TEC, hypoalbuminaemia, hypoprotienaemia and lower serum iron in ancylostomosis infected dogs. There is slight decrease in MCH, MCV and MCHC was observed in comparing with the healthy control. There was increase in TLC, N and E. In the treated groups after the institution of therapy there was some improvement in Hb, PCV, TEC, TPP, A, Serum iron. Eggs per gram (EPG) were performed before and on day 7th and day 15th post-treatment (DPT). Ivermectin and pyrantel pamoate was given as single dose administration @ 0.2 mg/kg S/C and 5 mg/kg per oral respectively. Examination before and after treatment revealed that the dogs which were naturally infected with A. caninum, based on EPG values, the efficacy were 100% against A. caninum following treatment with ivermectin and pyrantel pamoate on day 7 post treatment (PT) based on average reduction in EPG. On 15th day in pyrantel pamoate treated group, the mean EPG became 30 ± 30. So, pyrantel pamoate is marginally less effective than ivermectin | |
| dc.identifier.uri | http://krishikosh.egranth.ac.in/handle/1/5810064521 | |
| dc.keywords | Dogs, Ancylostomosis, Breeds, Prevalence, Anaemia, Haemato-biochemical, Ivermectin, Pyrantel pamoate, EPG | |
| dc.language.iso | English | |
| dc.pages | 79 + VITA | |
| dc.publisher | Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana | |
| dc.research.problem | Introduction, Review of literature, Materials and methods, Results and discussion, Summary, References, Vita | |
| dc.sub | Veterinary Medicine | |
| dc.these.type | M.V.Sc. | |
| dc.title | Haemato-biochemical and therapeutic studies on ancylostomosis in dogs | |
| dc.type | Thesis |
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