Evaluation of Pentazocine And Lorazepam With And Without Atropine In Caprine Surgery
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Date
1990
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Birsa Agricultural University, Ranchi
Abstract
1. Pentazocine + lorazepam+ atropine combination produces satisfactory sedation and moderate muscle relaxation in limited body area.
2. This combination exerts its influence in abolishing the superficial and deep cutaneous reflexes in the regions of abdomen, thorax and upper limbs permitting surgery in these areas.
3.Combination of only pentazocine and lorazepam does not exert satisfactory effects in terms of sedation, muscle relaxation and adequate analgesia-permitting surgery.
4.Side effects like tremor, intermittent convulsion,movement of jaw are observed in both combinations but they appear to be inconsequential and transitory.
5. Both an aesthetic regimen induce rise of body temperature 5.(1 to 2.2°F) which appears to be salutory during surgical intervention. This rise of temperature in more marked when atropine is used.
6. BUN and SGOT levels are only marginally affected with restoration of normalcy by six hours suggesting non toxic effects of the drug combinations on kidney and liver.
7. Evidence of sympathetic stimulation with both combinations is explicit resulting into accelerated heart rate and hyperglycemic features. Atropinization augments both these.
8.Reasonable limit of increased heart rate and moderate hyperglycemia appear to render beneficial effects during surgery under stress conditions.