Assessment of Anemia in Azotemic Dogs and it's Therapeutic Management
Loading...
Files
Date
2024-04-10
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
MAFSU, Nagpur
Abstract
Anemia is one of the most common signs of azotemia and has a
considerable influence on the progression and the prognosis of the disease. The
study was undertaken to assess the anemia of azotemic dogs and evaluate the
therapeutic management. 20 dogs were comprehensively reviewed in this study.
The age of the dogs ranged from 3 to 10 years and the highest affected age
groups were 4.75 to 6.5 years and 6.5 to 8.25 years (30% dogs each). Nondescript
dogs (45%) were the most affected. The range of body weight of the dogs
was 11.2 to 61.8 kg. Male dogs (75%) were more affected than female dogs
(25%) in the study. The clinical examination of the anemic dogs revealed 100%
dogs had pallor, 80% had vomition, 90% had dehydration, 60% had melena, 55%
had halitosis, 100% had anorexia/inappetence and 55% had polyuria/polydipsia.
The post-treatment hematobiochemical parameters revealed increased Hb
(61.75%), TEC (60.21%), PCV (55.64%), Platelets (43.17%), Ionic Calcium
(17.11%), Reticulocytes (14.75%), Absolute Reticulocyte Count (91.39%),
Corrected Reticulocyte Count (54.17%), RPI (110%), Serum Iron (15.67%), Iron
Saturation (22.76%) and decreased BUN (49.22%), Creatinine (46.72%),
Phosphorous (27.09%), TIBC (5.33%), Lactate (28%) and Systolic Blood
Pressure (8.3%) compared to pre-treatment values and significant difference was
noted between them. Nonsignificant observations were recorded in erythrocyte
indices, serum electrolytes, liver function test parameters and leucogram on Day
14 compared to Day 0. Reticulocyte count and Serum Iron showed a low positive
correlation. Serum Creatinine showed a high positive correlation with
Phosphorous and a moderate negative correlation with Ionic Calcium.
Normocytic, Normochromic and Non-regenerative anemia was the predominant
finding amongst the azotemic dogs. Low iron stores were recorded in 50% of the
dogs included in the study. Post therapeutic management, the azotemic dogs with
anemia showed considerable improvement in clinical signs and
hematobiochemical values.