COMPARISON OF APOPTOSIS IN STREET RABIES VIRUS ISOLATES AND CHALLENGE VIRUS STANDARD BY FLOWCYTOMETRY USING TUNEL STAINING METHOD
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Date
2018-02
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Scientific Research Forum
Abstract
Rabies is an avertable viral disease caused by the rabid animal to the warm
blooded animals especially human. The animals which are mainly reported as causes of
rabies are; dogs, raccoons, skunks, bats, and foxes. A study was undertaken to compare the
ability of Indian street rabies virus isolate and challenge virus Standard to induce apoptosis in
murine neuroblastoma cell line. Thirty Indian rabies virus isolates from infected street dogs
were tested by FAT used to infect Murine Neuroblastoma cell line (MNA) along with
Challenge Virus Standard (CVS). Expression of Caspase-1, Bad and Glycoprotein genes in
MNA cells in comparison with CVS. TUNEL staining method used to study the apoptotic
index of Street rabies virus and CVS was measured by using Flow cytometer.
Description
TNV_IJSET_2018_7(1)-138-142
Keywords
Veterinary Science, Preventive Medicine