Immune response to combined foot and mouth disease, haemorrhagic septicaemia and black quarter vaccine and their respective monovalent vaccines in cattle
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Date
2001
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Department of Veterinary Epideminology and Preventive Medicine, College of Veterinary and Animal Sciences,Mannuthy
Abstract
Immune response to combined Foot and Mouth Disease, Haemorrhagic Septicaemia and Black Quarter vaccine and to their respective individual vaccine were studied. Group I animals were vaccinated with combined FMD, HS and BQ oil adjuvant vaccine. Group Il animals were vaccinated with FMD polyvalent oil adjuvant vaccine and combined HS, BQ gel vaccine. Group III animals were vaccinated with polyvalent FMD oil adjuvant vaccine, HS gel vaccine and BQ gel vaccme. Vaccinations were done in unvaccinated calves above four month of age. Booster vaccination were carried out after nine month after primary vaccination for oil adjuvant vaccine and six month after primary vaccination for gel vaccine in all group animals. Monthly assessment of antibody titres against 0, A, C and Asia-l antigens were made by liquid phase blocking ELISA and Pasteurella multocida and Clostridium chauvoei by Indirect ELISA. All the three groups maintained protective antibody titre for FMD virus type '0', 'A', 'C~, 'Asia-l', Pasteurella multocida and Clostridium chauvoei antibody titres throughout the study period. All the three groups did not show any significant variation in antibody titres against FMDV type, '0', 'A', 'C' and 'Asia-L' and Pasteurella multocida and Clostridium chauvoei though they are well above protective titres. From this observation it is concluded that 1. All the three schedule of vaccination provides sufficient protective titre for FMDV type, '0', 'A', 'C' and 'Asia- l' and Pasteurella multo cid a and Clostridium chauvoei though they are well above protective titres. 2. Combined vaccine performance is equally good as that of individual vaccine. 3. Combined vaccine reduces labour cost for injection, number of visit and stress to the animals to a very great extent. There fore combined vaccine may be preferred
when compared to individual vaccine.
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