Diagnostic Evaluation of Left Apical Systolic Murmur In Dogs

dc.contributor.advisorPawalkar, D. A.
dc.contributor.authorGulati Mahima Vinod Kumar
dc.date.accessioned2024-10-30T09:50:53Z
dc.date.available2024-10-30T09:50:53Z
dc.date.issued2024-04-10
dc.description.abstractThe study entitled ‘DIAGNOSTIC EVALUATION OF LEFT APICAL SYSTOLIC MURMUR IN DOGS’ was carried out at CCDCU, at Department of Veterinary Medicine, Mumbai Veterinary College, Parel, Mumbai – 400012. Twenty-five dogs, with Left Apical Systolic Murmur and ten apparently healthy control dogs were included in study. Each dog underwent a thorough clinical, haemato-biochemical, radiographic, electrocardiographic and echocardiographic examination. Predominant clinical signs in study group were Exercise intolerance (40%), Orthopnoea (23%), Coughing (13%) and Ascites (11%) while 6/25 dogs exhibited no clinical signs. Significantly higher (p≤0.01) heart rate, respiratory rate and murmur grade were observed in non-survived group than survived group. Digital phonocardiogram proved valuable for diagnosing Left Apical Systolic Murmur, revealing a significant increase (p≤0.01) in the ratio of first (S1) to second (S2) heart sound in study group. Dogs with severe murmur had a nondiscernible second heart sound (S2). Significantly (p≤0.01) lower values of Hb, TEC, PCV and higher TLC, while significantly low (p≤0.05) albumin were observed in study group than control group. VHS and VLAS were significantly increased (p≤0.01) in the study group. Significantly higher (p≤0.01) VLAS was observed in non-survived dogs than survived dogs. VLAS had very high positive correlation with LA/Ao (r=0.82) and RF(r=0.84). VLAS ³2.2-2.4 was found to be a good indicator of LA enlargement. Predominant electrocardiographic changes observed were significantly increased P wave duration (p≤0.01) and PR interval (p≤0.05) in the non-survived group than survived group. On echocardiographic examination, 24/25 dogs reported degenerative changes of mitral valves. LA/Ao, LVIDdN, LVIDsN, MV E (m/s), MV E/A, RF and Tei values were significantly higher (p≤0.01) in non-survived group than survived group. MV E³1.2m/s and RF³50% were found to be good indicators of severe mitral regurgitation. Tei³0.59 was found to be associated with increased risk of cardiac death with 92% sensitivity and 75% specificity.
dc.identifier.urihttps://krishikosh.egranth.ac.in/handle/1/5810215982
dc.keywordsVeterinary Clinical Medicine
dc.keywordsEthics
dc.keywordsJurisprudence
dc.keywordsLeft Apical
dc.keywordsSystolic Murmur
dc.keywordsDog
dc.language.isoEnglish
dc.pages238
dc.publisherMAFSU, Nagpur
dc.subClinical Veterinary Medicine, Ethics and Jurisprudence
dc.themeLeft Apical Systolic Murmur In Dogs
dc.these.typeM.V.Sc.
dc.titleDiagnostic Evaluation of Left Apical Systolic Murmur In Dogs
dc.typeThesis
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