A STUDY ON THE ANTI-ARRHYTHMIC ACTIVITY OF DIPHENYL HYDANTOIN SODlUM
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Date
1977
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Abstract
The effects of Diphenyl hydantoin Sodium (DPH) on Cedilanid
induced cardiac arrhythmias were studied in dogs. The mean arrhythmogenic
dose(MAD) of Cedilamid was found to he 213±16.4 microgrammes
per Kilogram. DPH promptly reversed Cedilanid induced cardiac
arrhythmias into normal sinus rhythm but it lasted only for 3mts.
Repeated administration is necessary to prevent recurrence of arrhythmias
DPH at the rate of 1.6 mg/kg afforded significant protection
against Cediianid induced Cardiac arrhythmias.
Description
TNV_CRN_1977_6(2)170-174
Keywords
Veterinary Science