Comparative Pathology of Pyrethroid and Organophosphate Pesticides Intoxication in Mice and Goats
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Date
1987
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Birsa Agricultural University, Ranchi
Abstract
1.The clinical signs of chronic cypermethrin toxicity in mice appeared earliest in the Res depleted group and latest in RES activated group of mice. The cypermothrin treated normal mice fell between these two groups in exhibiting the clinical signs. Hyperesthesia, inco-ordination, irritation at the site of injection, paraplegia of hind quarters, respiratory distress, twitching of muscles, coma and death were observed in cypermathrin treated mice. On the other hand, the clinical signs of chronic quinalphos toxicity were dullness, depression, salivation, inco-ordination, prostration, coma and death.
2. The signs of chronic cypermethrin toxicity in goats were transitory in nature in two animals only which included hyperaesthesia, salivation and mild muscular tremors. Unlike cypermethrin the signs of chronic quinalphos toxicity in goats appeared early for a short period but the symptoms of toxicity in the terminal stages were more marked which included dullness, depression, salivation, diarrhoea, muscular tremor, posterior weakness, ataxia, dyspnoea, recumbency, groaning, coma and death .