Electrochemotherapy with intra-tumoral cisplatin for the treatment of fibrosarcoma in a horse
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Date
2019-04
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Abstract
A two years old Kathiawar stallion was reported with the history of two, pedunculated hard mass medially on the thigh and
hock of the right hind limb, progressively increasing for the past two months. Fine needle aspiration cytology revealed
fibrosarcoma.The tumour on the medial aspect of the thigh was injected with cisplatin intra-tumorally at a dose rate of 0.3
mg/cm3 of tumour volume and was exposed to ECT. The tumour on the medial aspect of the hock was excised incompletely
to preserve skin and subcutaneous tissues around the tumour for wound opposition and treated with intra-tumoral injection
of cisplatin followed by ECT. Following electrochemotherapy complete response was noticed onthe 3rd and 4th week for the
tumours on the thigh and hock respectively. No recurrence was noticed during the follow-up period of one year revealing
ETC with cisplatin as a single treatment and also in combination with surgery is effective for the treatment of fibrosarcoma
in equines.
Description
TNV_IJAR_2019_53(4)541-544
Keywords
Veterinary Science