Analgesic and isoflurane sparing effect of buprenorphine and butorphanol in cats anaesthetized with midazolam-ketamine-isoflurane
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Date
2019-08
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Abstract
A clinical study was conducted in 18 female cats subjected for ovariohysterectomy to access the analgesic and isoflurane
sparing effect of buprenorphine and butorphanol in cats anaesthetized with midazolam-ketamine- isoflurane. The cats were
divided into three Groups. In Group I, anaesthesia was induced by midazolam (@0.3mg/kg) ketamine (11mg/kg) mixture.
In Group II and Group III cats, butorphanol and buprenorphine were administered intramuscularly @ 0.4 mg/kg and 0.01
mg/kg, 15 minutes prior to induction of anaesthesia as in Group I. Anaesthesia was maintained with isoflurane. Inspired
fraction of isoflurane (FiISO) and End-tidal isoflurane (ETISO) in percentage were recorded by main stream infrared
spectroscopy analysis. The postoperative antinociceptive efficacy of drugs was studied by four point simple descriptive
scale (SDS) scoring system. The study on end-tidal isoflurane concentration revealed both buprenorphine and butorphanol
had reduced the use of isoflurane when compared to control group and among that butorphanol had a higher isoflurane
sparing effect than buprenorphine. The pain score study revealed buprenorphine produced adequate postoperative analgesia
when compared to butorphanol.
Description
TNV_IJAR_2019_53(8)1094-1096
Keywords
Veterinary Science