Congenital nephroblastoma in a Holstein-Friesian fetus - case report
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Date
2014
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Abstract
A seven-year-old Holstein-Friesian cow was brought to the hospital with signs of dystocia in the eighth
month of gestation. The dystocia was relieved and a dead male fetus removed. The fetus had a signifi cantly
distended abdomen. At necropsy, the fetus showed a very large, round and well encapsulated extra renal
mass in the abdominal cavity. The cut surfaces of the mass showed a white, caulifl ower-like growth with red
surfaces. The lobules were spongy and distinctly demarcated by fat and hemorrhages. Microscopic examination
of the tissue sections revealed blastemal, epithelial and mesenchymal elements. These cells were round to
oval in shape with scanty cytoplasm. The nuclei were spherical, sometimes vesicular and hyperchromatic.
The epithelial structures resembled the development of tubulo-glomerulogenesis. The mesenchymal cells were
polyhedral in shape, found between the tubules. The gross and microscopic features of the tissue sections were
consistent with a diagnosis of nephroblastoma.
Description
TNV_IVJ_2014_84(2)199-204
Keywords
Veterinary Science