Progressive light microscopic changes in chronic recurrent outbreaks of hepatic coccidiosis in domestic rabbits
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Date
2018
Journal Title
Journal ISSN
Volume Title
Publisher
TANUVAS
Abstract
Hepatic coccidiosis is an important economic disease of rabbits. The progressive
histopathological changes in liver of rabbits infected with Eimeria stiedae in chronic
recurrent outbreaks of coccidiosis in organized rabbitries are discussed. One hundred
and fifty morbid specimens of rabbit liver samples from known cases of hepatic coccidiosis
preserved in 10% formalin were studied. The hepatic parenchyma revealed multifocal
areas of coagulative to liquefactive necrosis, congestion, haemorrhages and vacuolar
degenerative changes in hepatocytes along with periportal infiltration of numerous
lymphocytes and a few neutrophils. Biliary ducts were hyperplastic with pappilomatous
ingrowths of epithelium into lumen. In chronic infections, multifocal areas of severe
periportal cirrhosis with islands of hepatic parenchyma were seen along with extensive
infiltration of lymphocytes, plasma cells and macrophages and prominent calcification
of bile ducts. Gall bladder epithelium also showed early lesions of hyperplasia of
epithelial cells in mucosa with necrosis and severe inflammation and extensive fibrosis.
The intensive growing conditions and contributory factors like high humidity, moisture,
feeding and manure disposal system may lead to recurrent outbreaks of hepatic
coccidiosis in rabbits.
Description
TNV_JVP_2018_32(2)78-81
Keywords
Veterinary Science