Treatment of bovine postpartum clinical endometritis through fixed dose-contact time intrauterine direct ozone insufflation
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Date
2017
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Orissa University of Agriculture and Technology, Bhubaneswar
Abstract
The aim of the present study was to evaluate the effect of intrauterine ozone
insufflation alone or in combination with cephalexin in treating the postpartum clinical
endometritis in dairy cows. Fourteen postpartum clinical endometric cows based on the
uterine findings and diagnosis were randomly allotted into two groups (each seven in number)
and seven postpartum normal cyclic animals were taken as control. Animals in group I were
treated with intrauterine ozone insufflation. Group II animals were treated with cephalexin
(Lixen-IU®) through intrauterine route in combination with intrauterine ozone insufflation and
the animals in control group were not subjected to any treatment regimen. After clinical
recovery, the animals were inseminated artificially on exhibition of estrus. Combined mucous
character and odour, PMN cell count and bacterial count were assessed on pre and post
treatment days and the conception rate was evaluated following first artificial insemination.
Following treatment the overall reduction in combined mucous character and odour both in
group I (82.04%) and group II (87.25%) were similar and highly significant (p<0.01). The
most predominant bacteria found was E. coli (28.57%) followed by Pseudomonas spp.
(14.28%), Staphylococcus spp. (21.42%), Streptococcus spp. (21.42%), Proteus spp. (7.14%)
and Acinetobacter calcoaceticus (7.14%). Overall reduction in bacterial count on pre (day 1)
and post treatment (day 7) were highly significant (p<0.01) i.e. 99.60% in group I and 99.72%
group II. PMN cell counts of uterine smear were significantly (p<0.01) increased from pre
treatment (25.85±3.28 in group I and 22.85±2.77) in group II) to post treatment (77.71±2.86
in group I and 87.14±1.35 in group II) which indicated the infiltration of neutrophils due to
action of ozone and cephalexin. The conception rates following first AI were recorded as
42.85% in group I (3/7) and 71.42% (5/7) in group II. Thus intrauterine ozone insufflation has
the potential to alleviate postpartum clinical endometritis as an efficacious, cost effective
treatment option and an alternative to antibiotics with an overall improvement of fertility rate
in dairy cows.
Description
Th-5619
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