New castle disease is a viral disease caused by Avulavirus, which has a worldwide distribution and is regarded as one of the most important constraint to the development of backyard poultry production. It causes immunosuppression in birds so it predispose bird to get other viral or bacterial diseases. Forty percent mortality was recorded in a backyard desi poultry farm. Before death, the birds were depressed, inappetant, dull and had occulonasal discharge, torticolis and open mouth breathing. One bird was presented for complete necropsy examination at Department of Veterinary Pathology, MVC, Chennai-07.