In Vitro Evaluation of Natural Keratin Based Hydrogel from Chicken Feather Waste for Controlled Drug Release
Loading...
Date
2018-10
Journal Title
Journal ISSN
Volume Title
Publisher
Excellent Publishers
Abstract
In the present study keratin was extracted from chicken feather using the
reductants beta mercaptoethanol, urea and SDS. The extracted keratin was
lyophilised and was used to prepare hydrogel. Prepared hydrogel was
characterized using SEM and FTIR. The prepared keratin hydrogel was
used for encapsulation of tetracycline. The percentage of drug
encapsulation in keratin hydrogel was found to be 92.5%. The in vitro
release of tetracycline from keratin hydrogel was carried out in PBS for
24hrs and was found to be released in a slow and sustained manner.
Description
TNV_Ijcmas_2017_6(10)3488-3495
Keywords
Veterinary Science