Evaluation of therapeutic effect of metoclopramide in gastrointestinal tract atony in buffaloes
Abstract
Gastrointestinal atony exits as one of the most common digestive tract ailments among
buffaloes which results in great loss of economy. Present experiment was conducted to evaluate
clinico-haematobiochemical and ruminal fluid parameters in affected animals (n=50) and also to study
therapeutic effect of metoclopramide in gastrointestinal tract atony in buffaloes (n=12). Mean age of
buffaloes affected with non-traumatic gastrointestinal tract atony was 5.67±0.44 years and duration of
illness was 10.86±0.96 days. Animals brought to the VCC with complaint of inappetance/anorexia,
reduced or loss of defecation with or without mucus and melena, colic signs and loss of production.
Haemato-biochemical evaluation revealed neutrophilia, lymphopenia, hypocalcaemia, hypochloraemia,
hypokalaemia, hyperglycemia with increased aspartate aminotransferase level in all affected animals.
Ruminal fluid analysis revealed reduced to absent microbial activity with delayed MBRT and SFT and
increased ruminal chloride concentration indicating abomasal reflux. Dialated and impacted portion of
caecum and colon were palpated per-rectally with dialated loops of intestine in pelvic cavity or in front
of pelvic brim. Per-rectally dialated loops of intestine were palpated in cases not responding to
conservative medicinal treatment. For therapeutic evaluation clinical cases were divided into two
groups {group I (n=6) - Hypertonic saline and Calcium; group II (n=6) - Metoclopramide, Hypertonic
saline and Calcium}. Three animals were found to be recovered in group I and four in group II. Present
study concluded that Combination of hypertonic saline, calcium and metoclopramide was the most
effective treatment group in gastrointestinal tract atony in buffaloes.
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