Hepatoprotective Activity of Caralluma umbellata in Chicken
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Date
2014-12
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Abstract
Hepatoprotective activity of Caralluma umbellata
on paracetamol induced hepatotoxicity was
evaluated in white leghorn male cockerels. They
were divided into five groups of six birds each.
Birds in group I served as untreated control.
Group II was administered with paracetamol
@ 2 g/kg body weight orally from seventeenth
day and till the end of the experiment. Group
III was given silyamin @ 100mg/kg for 16 days
followed by paracetamol @ 2 g/kg body weight
till the end of the experiment. Group IV and V
were administered with Caralluma umbellata @
500mg and 2500 mg/kg body weight for 16 days
followed by paracetamol @2 g/kg body weight.
Hemato-biochemical observations were made.
The cytopathology of the liver was also recorded
in all the groups treated. Hemato-biochemical
observations and cytopathology showed the
reversal of paracetamol induced toxicity by
Caralluma umbellata.
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Keywords
Veterinary Science, Animal Reproduction, Gynaecology and Obstetrics