Diagnostic and Therapeutic Management of Diabetes Mellitus in Canine
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Date
2017
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MAFSU Nagpur
Abstract
The study entitled ‘ Diagnostic and therapeutic management of diabetes
mellitus in canine” was carried out at the Teaching Veterinary Clinical Complex
(TVCC)and Department of Veterinary Clinical Medicine, Ethics & Jurisprudence,
Nagpur Veterinary College, Nagpur. The dogs presented at TVCC with symptoms of polyuria, polydipsia, polyphagiaand obesity of 5 years and random blood glucose more than 150mg/dl were includedin the study. Total 642 dogs showing typical symptoms of diabetes were screened. The
data revealed the prevalence of 1.86 %. The highest occurrence was observed in
Labrador (58.33 %), followed by Spitz (16.66 %) and 8.33 % each of Dachshund,
Mongrel and Golden Retriever. Females were more affected as compare to
males. The common clinical symptoms included polyuria, polydipsia, polyphagia,
obesity and lethargy. In one case, bilateral cataract was noticed whereas in four
cases renal affections were noted. Screened dogs were divided into two groups comprising of six animals in
each group.Group I Dogs diabetes mellitus treated with a therapeutic regimen
consistinga combination of Syrup Activated Zinc, Activated Arginine, Calcium
Pantothanate L carnitine and lettuce extract @ 1 ml / 5 kg body weight.Group
IIDogs diabetes mellitus were treated with recombinant insulin, @ 0.5 IU/kg, i/m,
after meal at every 12 hrs interval. The haematobiochemical parameters
indicated that the random and pre-prandial blood glucose levels did not differ
significantly within the groups or between the groups. However, the dogs
responded to recombinant insulin and post-prandial blood glucose levels
significantly reduced in this group. There was no significant effect on Serum Cholesterol, Serum Triglyceride,
and BUN in any of the groups. The haematological parameters such as TLC, Haemoglobin, PCV
andTEC and biochemical parameter Serum Creatinine, did not show any
significant difference within the days and between the groups. However, there
was signifant differences in the values of neutrophil and lymphocyte counts in
both the groups. The urinalysis indicated traces of glucose in all dogs and
Ketonuria and proteinuria in 33.33 per cent cases, each. The urine samples
revealed the presence E. Coli in 33% cases.
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