Clinical Efficacy of Anaesthetic Regimens Using Etomidate and Propofol in Dogs
Loading...
Date
2017
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Rajasthan University of Veterinary and Animal Sciences, Bikaner
Abstract
The present study was conducted on 20 dogs of both sexes with various surgical affections were randomly assigned to 2 anaesthetic induction groups (n=10) after premedication with glycopyrrolate (0.01 mg/kg; IM) followed by midazolam (0.25 mg/kg; IV) 15 min later. In group A, etomidate (1.46 mg/kg; IV) produced excellent to good induction with average score 3.80 ± 0.13. In group B, propofol (4.68 mg/kg; IV) produced good to excellent with average score 3.70±0.15. Induction with etomidate and propofol resulted in the alterations in various clinical, physiological and haemato-biochemical parameters observed in both group A and B. Rectal temperature showed significant decreasing trend just after induction, at 5 minute and 10 minute in group A and significantly decreased throughout the anaesthesia in group B from the base line value. Other parameters showed non-significant changes at different time intervals. Recovery was satisfactory in both the groups and was recorded faster (5.60±0.56 min) in group A as compared to group B (7.9±0.55 min). The quality of recovery had better score (3.80±0.13) in group A than group B (3.6±0.22) The average score for quality of ataxia recorded in group A was 3.6±0.22 compared to 3.1±0.23 in group B. Adverse signs reported during induction were pain on injection, myoclonus, hypersalivation, and transient apnoea and during recovery, excitement and paddling were observed. However, yawning was observed as a specific finding in all the animals of group A during induction of anaesthesia with etomidate. Overall observations showed that etomidate could be a satisfactory alternative to propofol in situations where short duration anaesthesia with minimal cardio-pulmonary depression is desirable.
Description
Keywords
null