CLINICAL EPIDEMIOLOGY, HAEMATO-BIOCHEMICAL ALTERATIONS, DIAGNOSIS AND THERAPEUTIC MANAGEMENT OF PARVOVIRUS INFECTION IN CANINE
Loading...
Date
2011
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Sher-e-Kashmir University of Agricultural Sciences and Technology of Jammu
Abstract
Studies on clinical epidemiology, diagnosis, haemato-biochemical alterations and therapeutic management of canine parvovirus infection in canine from clinics of Jammu were conducted during July, 2008 to June, 2009. Faecal samples of 158 dogs with gastroenteritis were subjected to Haemagglutination (HA), Haemagglutination Inhibition (HI) and Polymerase Chain Reaction (PCR) with CPV positivity as 29.11, 24.68 and 51.9 per cent, respectively. Season-wise prevalence was 85.71% during December (highest), 80% in January and zero in June; age wise highest in > 6 months (57.62%) and lowest (40%) in 0-3 months with no difference amongst sex. Breed wise, Labrador had highest prevalence (73.52%), followed by German Shepherd (66.66%), Pomeranian (61.9%), Doberman (46.66%) and Non-descript (30.61%). Clinico-haematological profile of CPV infected dogs revealed statistically significant decrease in mean haemoglobin, packed cell volume, total erythrocyte count, total leucocyte count. Erythrocytic indices and platelet count were low as compared to healthy control. Differential leucocyte count revealed lymphopaenia with relative neutrophilia. Haemato-biochemical profile showed hyponateremia, hypokalaemia, hypochloremia with decrease in total serum protein, serum albumin, A/G ratio and an increase in BUN values. Comparable increase in mean value of alkaline phosphate and SGPT as compared to healthy control was recorded. Reduction in clinical score and recovery of all clinico-haematobiochemical values was the basis of assessment of therapeutic response in CPV infected dogs. Treatment Tl with Pet Alive Parvo-K, antibiotic, rehydration therapy need based and supportive therapy showed higher (75%) recovery rate as compared to Treatment 2: Parvo-K, antibiotic and need based rehydration therapy (35 %).
Key Words: Clinical epidemiology, diagnosis, haemato-biochemical alterations, therapeutic management, CPV, therapeutics, Pet Alive Parvo-K
Description
Keywords
null
Citation
No. of references 256