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Birsa Agricultural University, Ranchi

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Subject: Veterinary Surgery and Radiology × End date: 2007 ×
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Now showing 1 - 9 of 11
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    ThesisItemOpen Access
    Comparative Evaluation of Bupivacaine, Zylazine and Xylocanine for Lumbo- sacral epidural Anesthesia in Pigs
    (Birsa Agricultural University, Ranchi, 2001) Vinod kumar; P.N.B.Sahay
    1.Xylocaine @ 1 ml/5 kg body weight produced moderate analgesia and sedation permitting surgery of short duration. 2.Xylazine @ 3 mg/kg body weight produced moderate analgesia and satisfactory sedation permitting surgery of comparatively longer duration than that of Xylocaine. 3. Bupivacine @ 2 ml/5 kg body weight produced excellent analgesia, satisfactory sedation and deep muscle relaxation for a longer period, facilitating surgery of varying magnitude and longer duration upto posterior thoracic region. 4. Hyperglycemia was not a consistent feature following epidural administration of the anaesthetic agents. Variable levels of elevation in different groups was mild, transient in nature and normalcy could be restored in all the animals by 24 hours. 5.Serum creatinine, urea and AST level manifested alterations within. the physiological range even though at some stages of observation they were statistically significant. 6. Hypothermia was not a feature with Xylocaine and Bupivacaine. anaesthesia. Moderate rise in temperature with these agents was well compensated by 120 minutes. However, administration of Xylazine induced significant hypothermia. 7. Safe and satisfactory anaesthesia could be induced at the dose levels evaluated in this experiment to facilitate surgery of post thoracic regions employing Bupivacaine, Xylazine and Xylocaine in that order.
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    ThesisItemOpen Access
    Evaluation of The Fentanyl And Its Combination With Droperiodol And Haloperidel For Epidural Analgesia -in Dogs
    (Birsa Agricultural University, Ranchi, 2001) Sanjay Kumar; L.L. Das
    Hypothermia was a consistent feature of narcotic analgesic (fentanyl) and neuroleptanalgesic, however, decreasing trend in body temperature was marginal and short lived. Bradycardia and bradypnoea are the regular features of neuroleptanalgesia however, these are preceded by an appreciable increase in heart and pulse rate. Epidural administration of fentanyl @ 0.01 mg/kg induced optimal sedation but intense analgesia and relaxation could be observed for 30 minutes. muscle Sedation, analgesia and muscle relaxation were variant in two combinations. Fentanyl + droperidol produced excellent sedation and analgesia with optimum muscle relaxation for nearly 1 hour, while fentanyl + haloperidol produced satisfactory analgesia and sedation for about 70 minutes. The combination of fentanyl with droperidol and haloperidol evinced abolition of superficial and deep cutaneous reflexes over a wider region of body, permitting surgery of different magnitude, than fentanyl alone.. In terms of duration of effect and magnitude of muscle relaxation, combination seemed to be superior. It is suggested that surgery under stress condition may be performed of fentanyl and its combination with droperidolo/haloperidol. Aspartate transaminase, blood urea nitrogen and creatinine levels exhibited non-significant alterations within normal physiological limits and suggested non-toxic effect of the anaesthetic regimens on liver, kidney, muscles and heart. The increasing trend of glucose observed in all groups was transitory and marginal and hence neuroleptanalgesia can be safely employed in both hyper- and hypoglycaemic patients.
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    ThesisItemOpen Access
    Lumbosacral Epidural Analgesia Induced By6 Xylazine Katamine And Their Combination In Goats A Comparative Study
    (Birsa Agricultural University, Ranchi, 2000) Prem Chand Sao; P.N. Sahay
    .Xylazine @ 0.10 mg/kg, Ketamine @ 8 mg/kg and their combination @ 0.05 mg/kg + 6 mg/kg produced moderate analgesia and satisfactory sedation permitting surgery of short duration. (2) The combination @0.10 mg/kg + 8 mg/kg of Xylazine and Ketamine respectively, induced excellent analgesia, deep. sedation and optimum muscle relaxation for a longer period facilitating surgery of varying magnitude and longer duration in the posterior thoracic region. (3) The other five dose schedules (0.02 mg/kg, 0.05 mg/kg of Xylazine, 4 mg/kg, 6 mg/kg of Ketmine and 0.02 mg/kg + 4 mg/kg of combination were not found satisfactory due to one or the other shortcomings, viz., lack of sedation, very mild analgesia, inadequate muscle relaxation etc. (4) Dose dependent hyperglycaemia was a consistent feature following epidural administration of the anaesthetic agents. alone or in combination. This was transient in nature as there was evidence of normalisation by 24 hours.
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    ThesisItemOpen Access
    Evaluation of Ketamine and Its Combination with Diazepam and Lorazepam in Caprin Surgery
    (Birsa Agricultural University, Ranchi, 1997) Shailendra Kumar Singh; P.N. sahay
    1. Ketamine alone @ 12 mg/kg body wt. induced optimal sedation but very poor analgesia and muscle relaxation in a limited area of the body. 2.Ketamine + diazepam in atropinized goats produced satisfactory sedation, adequate muscle relaxation and optimal analgesia, with smooth induction.. 3.There was abolition of superficial and deep cutaneous reflexes over a wider region of the body permitting surgery of different magnitudes with diazepam ketamine. 4.With Ketamine and lorazepam combination, there was rough induction, unsatisfactory muscle relaxation and analgesia even though sedation was moderate. 5. Hyperglycaemia of varying magnitude was a consistent feature of ketamine anaesthesia and its combination with diazepam and lorazepam. 6.BUN, ALT and AST levels exhibited alterations within the normal physiological limits and suggested non-toxic effect of the anaesthetic regimens on kidney, liver and heart. 7.Atropinization quality of did not seemed to be affecting anaesthesia, even though it countered side effects of ketamine effectively. 8.There was evidence to suggest that surgery stress conditions may be performed with diazepam combination in atropinized goats.
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    ThesisItemOpen Access
    Evaluation of Ketamine and Its Combination With Xylazine And Promazine For Anesthesia in Goats
    (Birsa Agricultural University, Ranchi, 1994) Lalit Kumar Ekka; L.L. Dass
    1.Ketamine alone produces optimal sediation and analgesia for a short duration but inadequate muscle relaxation in the goats. 2. Combination muscle of promazine produces mild degree of muscle relaxation apart from prolonging of the duration of action. 3.When xylazine and ketamine are administered, there is adequate muscle relaxation and abolition of superficial and deep cutaneous reflexes permitting surgery of varying magnitude. 4.Moderate hyperglycaemia is a feature of anaesthesia appeares to render beneficial effects during surgery under stress conditions. 5.As evidenced by the estimations of SGOT, BUN, creatinine and haematological as well as clinical parameters, ketamine and its combinations are safe for anaesthesia in goats.
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    ThesisItemOpen Access
    Evaluation Of Neuroleptanalgesia In Bovine
    (Birsa Agricultural University, Ranchi, 1990) Dass, Laliteshwar Lal; P.N. Sahay
    Three different combinations of neuroleptics and narcotic analgesics, constituting neuroleptanalgesics, were evaluated in 18 clinically healthy male cow calves, aged one to one and a half years. The animals were divided randomly into three groups of six animals each. In group I, combination of meperidine and promazine was injected. In group II, meperidine and diazepam were used together. In group III, Innovar-Vet was administered. Meperidine, promazine and diazepam were used at a dose rate of 12 mg, 3 mg and 1 mg per kilogram body weight respectively while Innovar-Vet 0.5 ml/10 kg by dow 1/v injection. Clinical observations, haematological and biochemical alterations including van den Bergh test were studied prior to the administration of neuroleptanalgesic and at 5, 15, 30, 60 and 120 minutes following induction of neuroleptanalgesia (NLA). Finally these parameters were evaluated at 24 hours of drug injection. Venous blood samples were collected at these time intervals. Mean arterial pressure, central venous pressure and heart rate vere measured at the periods specified above except the former two at 24 hours. For the estimation of cardiac output (a) arterial blood samples were collected after 1/v injection of Evans blue dye at 0 minute, and at 5, 30 and 120 minutes of administration of anaesthetics. The parameters related to a viz., cardiac index, stroke volume, total peripheral resistance, stroke index were computed with the help of other measured parameters like MAP, heart rate, body surface area, venous haematocrit etc.
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    ThesisItemOpen Access
    Evaluation of Pentazocine And Lorazepam With And Without Atropine In Caprine Surgery
    (Birsa Agricultural University, Ranchi, 1990) Maji, Asit Kumar; U. K. Deokiouliyar
    1. Pentazocine + lorazepam+ atropine combination produces satisfactory sedation and moderate muscle relaxation in limited body area. 2. This combination exerts its influence in abolishing the superficial and deep cutaneous reflexes in the regions of abdomen, thorax and upper limbs permitting surgery in these areas. 3.Combination of only pentazocine and lorazepam does not exert satisfactory effects in terms of sedation, muscle relaxation and adequate analgesia-permitting surgery. 4.Side effects like tremor, intermittent convulsion,movement of jaw are observed in both combinations but they appear to be inconsequential and transitory. 5. Both an aesthetic regimen induce rise of body temperature 5.(1 to 2.2°F) which appears to be salutory during surgical intervention. This rise of temperature in more marked when atropine is used. 6. BUN and SGOT levels are only marginally affected with restoration of normalcy by six hours suggesting non toxic effects of the drug combinations on kidney and liver. 7. Evidence of sympathetic stimulation with both combinations is explicit resulting into accelerated heart rate and hyperglycemic features. Atropinization augments both these. 8.Reasonable limit of increased heart rate and moderate hyperglycemia appear to render beneficial effects during surgery under stress conditions.
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    ThesisItemOpen Access
    Evaluation Of Pentazocine Alone And In Combination With Diazepam In Goats
    (Birsa Agricultural University, Ranchi, 1989) Bhattacharya, Sabysachi; P.N. Sahay
    On the basis of the present experimental study, the following conclusions are drawn: 1. Pentazocine and diazepam combination produces optimal sedation but narrow range muscle relaxation in goats. 2. Abolition of superficial and deep cutaneous reflexes, permitting surgical intervention, without impairment of consciousness, are restricted to the limbs and abdomen. 3. Pentazocine alone does not exert its influence, to clinically satisfactory level, on any feature as indicated in sl. no. 1 and 2 above. 4. Fall in rectal temperature with combination is explicit but hypothermia does not appear to be a characteristic of pentazocine administration. 5. Hematological profile appears to be convince ingly altered in some of the parameters by either means of administration, but these are transitory. 6. SGOT changes in response to pentazocine or its diazepam combination may suggest involvement of liver, but the effects being short-lived and within physiological limits make them to be inconsequential. 7. There may be fluctuating rise and fall in blood glucose level but these are not sustained to constitute hyper or hypoglycemic states in goats. 8. Finally, pentazocine may be very potent in alleviating all types of pain, its ability to prevent induced pain is conjectural.
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    ThesisItemOpen Access
    EVALUATION OF AUTOLOGOUS BONE MARROW ALONE AND IN COMBINATION WITH PULVERIZED BONE FOR PROMOTING THE HEALING OF COMPOUND FRACTURE IN GOATS
    (Birsa Agricultural University, 1988) MUKHEJEA, RUDRADEV; Sahay, P.N.
    On the basis of the results obtained in the present investigation the following conclusion are being dran 1. Proper reduction and immobilization along with suitable biological materials can achieve the healing of compound fracture in optimal time. 2. She autologous bone marrow and homologous pulverized bone were found to have definite role in promoting osteogenesis. 3. In the present study combined therapy of bone marrow and pulverized bone appears to be superior to the use of bone marrow alone on the basis of clinical, radiological and histonorphological findings. 4. Bone marrow alone, though exerts influence in the healing of compound fracture, its role appears to be minimal. Compound fracture healing without support of osteoinducers is associated with manifolds problems. 5. Both the biological materials used in this study can be easily employed without any detrimental effect and thus can be easily practiced in field conditions. 6. The concept that the process of compound fracture healing is augmented by application of biological inducers has been confirmed by the results of this study.