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Birsa Agricultural University, Ranchi

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1986 - 198941990 - 19974
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Subject: Veterinary Surgery and Radiology × End date: 1997 × Type: Thesis ×
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Now showing 1 - 8 of 8
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    ThesisItemOpen Access
    Evaluation of Ketamine and Its Combination with Diazepam and Lorazepam in Caprin Surgery
    (Birsa Agricultural University, Ranchi, 1997) Shailendra Kumar Singh; P.N. sahay
    1. Ketamine alone @ 12 mg/kg body wt. induced optimal sedation but very poor analgesia and muscle relaxation in a limited area of the body. 2.Ketamine + diazepam in atropinized goats produced satisfactory sedation, adequate muscle relaxation and optimal analgesia, with smooth induction.. 3.There was abolition of superficial and deep cutaneous reflexes over a wider region of the body permitting surgery of different magnitudes with diazepam ketamine. 4.With Ketamine and lorazepam combination, there was rough induction, unsatisfactory muscle relaxation and analgesia even though sedation was moderate. 5. Hyperglycaemia of varying magnitude was a consistent feature of ketamine anaesthesia and its combination with diazepam and lorazepam. 6.BUN, ALT and AST levels exhibited alterations within the normal physiological limits and suggested non-toxic effect of the anaesthetic regimens on kidney, liver and heart. 7.Atropinization quality of did not seemed to be affecting anaesthesia, even though it countered side effects of ketamine effectively. 8.There was evidence to suggest that surgery stress conditions may be performed with diazepam combination in atropinized goats.
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    ThesisItemOpen Access
    Evaluation of Ketamine and Its Combination With Xylazine And Promazine For Anesthesia in Goats
    (Birsa Agricultural University, Ranchi, 1994) Lalit Kumar Ekka; L.L. Dass
    1.Ketamine alone produces optimal sediation and analgesia for a short duration but inadequate muscle relaxation in the goats. 2. Combination muscle of promazine produces mild degree of muscle relaxation apart from prolonging of the duration of action. 3.When xylazine and ketamine are administered, there is adequate muscle relaxation and abolition of superficial and deep cutaneous reflexes permitting surgery of varying magnitude. 4.Moderate hyperglycaemia is a feature of anaesthesia appeares to render beneficial effects during surgery under stress conditions. 5.As evidenced by the estimations of SGOT, BUN, creatinine and haematological as well as clinical parameters, ketamine and its combinations are safe for anaesthesia in goats.
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    ThesisItemOpen Access
    Evaluation Of Neuroleptanalgesia In Bovine
    (Birsa Agricultural University, Ranchi, 1990) Dass, Laliteshwar Lal; P.N. Sahay
    Three different combinations of neuroleptics and narcotic analgesics, constituting neuroleptanalgesics, were evaluated in 18 clinically healthy male cow calves, aged one to one and a half years. The animals were divided randomly into three groups of six animals each. In group I, combination of meperidine and promazine was injected. In group II, meperidine and diazepam were used together. In group III, Innovar-Vet was administered. Meperidine, promazine and diazepam were used at a dose rate of 12 mg, 3 mg and 1 mg per kilogram body weight respectively while Innovar-Vet 0.5 ml/10 kg by dow 1/v injection. Clinical observations, haematological and biochemical alterations including van den Bergh test were studied prior to the administration of neuroleptanalgesic and at 5, 15, 30, 60 and 120 minutes following induction of neuroleptanalgesia (NLA). Finally these parameters were evaluated at 24 hours of drug injection. Venous blood samples were collected at these time intervals. Mean arterial pressure, central venous pressure and heart rate vere measured at the periods specified above except the former two at 24 hours. For the estimation of cardiac output (a) arterial blood samples were collected after 1/v injection of Evans blue dye at 0 minute, and at 5, 30 and 120 minutes of administration of anaesthetics. The parameters related to a viz., cardiac index, stroke volume, total peripheral resistance, stroke index were computed with the help of other measured parameters like MAP, heart rate, body surface area, venous haematocrit etc.
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    ThesisItemOpen Access
    Evaluation of Pentazocine And Lorazepam With And Without Atropine In Caprine Surgery
    (Birsa Agricultural University, Ranchi, 1990) Maji, Asit Kumar; U. K. Deokiouliyar
    1. Pentazocine + lorazepam+ atropine combination produces satisfactory sedation and moderate muscle relaxation in limited body area. 2. This combination exerts its influence in abolishing the superficial and deep cutaneous reflexes in the regions of abdomen, thorax and upper limbs permitting surgery in these areas. 3.Combination of only pentazocine and lorazepam does not exert satisfactory effects in terms of sedation, muscle relaxation and adequate analgesia-permitting surgery. 4.Side effects like tremor, intermittent convulsion,movement of jaw are observed in both combinations but they appear to be inconsequential and transitory. 5. Both an aesthetic regimen induce rise of body temperature 5.(1 to 2.2°F) which appears to be salutory during surgical intervention. This rise of temperature in more marked when atropine is used. 6. BUN and SGOT levels are only marginally affected with restoration of normalcy by six hours suggesting non toxic effects of the drug combinations on kidney and liver. 7. Evidence of sympathetic stimulation with both combinations is explicit resulting into accelerated heart rate and hyperglycemic features. Atropinization augments both these. 8.Reasonable limit of increased heart rate and moderate hyperglycemia appear to render beneficial effects during surgery under stress conditions.
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    ThesisItemOpen Access
    Evaluation Of Pentazocine Alone And In Combination With Diazepam In Goats
    (Birsa Agricultural University, Ranchi, 1989) Bhattacharya, Sabysachi; P.N. Sahay
    On the basis of the present experimental study, the following conclusions are drawn: 1. Pentazocine and diazepam combination produces optimal sedation but narrow range muscle relaxation in goats. 2. Abolition of superficial and deep cutaneous reflexes, permitting surgical intervention, without impairment of consciousness, are restricted to the limbs and abdomen. 3. Pentazocine alone does not exert its influence, to clinically satisfactory level, on any feature as indicated in sl. no. 1 and 2 above. 4. Fall in rectal temperature with combination is explicit but hypothermia does not appear to be a characteristic of pentazocine administration. 5. Hematological profile appears to be convince ingly altered in some of the parameters by either means of administration, but these are transitory. 6. SGOT changes in response to pentazocine or its diazepam combination may suggest involvement of liver, but the effects being short-lived and within physiological limits make them to be inconsequential. 7. There may be fluctuating rise and fall in blood glucose level but these are not sustained to constitute hyper or hypoglycemic states in goats. 8. Finally, pentazocine may be very potent in alleviating all types of pain, its ability to prevent induced pain is conjectural.
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    ThesisItemOpen Access
    EVALUATION OF AUTOLOGOUS BONE MARROW ALONE AND IN COMBINATION WITH PULVERIZED BONE FOR PROMOTING THE HEALING OF COMPOUND FRACTURE IN GOATS
    (Birsa Agricultural University, 1988) MUKHEJEA, RUDRADEV; Sahay, P.N.
    On the basis of the results obtained in the present investigation the following conclusion are being dran 1. Proper reduction and immobilization along with suitable biological materials can achieve the healing of compound fracture in optimal time. 2. She autologous bone marrow and homologous pulverized bone were found to have definite role in promoting osteogenesis. 3. In the present study combined therapy of bone marrow and pulverized bone appears to be superior to the use of bone marrow alone on the basis of clinical, radiological and histonorphological findings. 4. Bone marrow alone, though exerts influence in the healing of compound fracture, its role appears to be minimal. Compound fracture healing without support of osteoinducers is associated with manifolds problems. 5. Both the biological materials used in this study can be easily employed without any detrimental effect and thus can be easily practiced in field conditions. 6. The concept that the process of compound fracture healing is augmented by application of biological inducers has been confirmed by the results of this study.
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    ThesisItemOpen Access
    ROLE OF AUTOGENOUS CANCELLOUS AND HOMOGENOUS DECALCIFIED BONE CHIPS IN THE REPAIR OF COMPOUND FRACTURE IN GOATS
    (Birsa Agricultural University, 1988) GHOSH, DEBAKI; DEOKIOULIYAR, U.K.
    On the basis of the results obtained in this study the following conclusions have been drawn: 1. Autogenouscancellous tissues employed locally in the treatment of compound fracture enhancesosteogenesis, which facilitates union in optimal time by the growth of compact, firm osseous tissue. 2. Collection of cancellous material from the rib is easy and devoid of any expenditure and major intervention on animal’s body. Thus it can be practiced widely in rural condition. 3. Since cancellous tissue contains maximum number of osseous cells and occupies interfragmentary space, it initiates better neo-osteogenesis. 4. Homogenous decalcified tissue appeared to be good as supporting tissue and thus it evidenced better osteoinductive property. 5. Doth the bone inducers appeared to shorten the healing phase in compound fracture but autogenouscancellous chips are superior to the homogenous decalcified tissue. 6. Notwithstanding the relative merits of osteoinduction, both the biological materials appear to possess the capability to proclule infection during the healing of compound fracture in goats.
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    ThesisItemOpen Access
    STUDIES ON DYNAMICS OF BONE HEALING BY THE ADMINISTRATION OF CERTAIN BONE INDUCERS IN CAPRINE
    (Birsa Agricultural University, 1986) Singh, DAMODAR PRASAD; KHAN, A.A.
    1. Suitable inducing agents can accelerate the healing of fractured bone after its adequate reduction and inmobilisation. 2. The drugs, chemicals and herbal plant selected for this study were found to have definite role in promoting osteogenesis. 3. In the present dose schedule the combined therapy of zinc sulphate plus ascorbic acid appears to be superior among the four inducers used for this study. 4. Ciscusquadrangularis and tonophosphan ranked second and third in terms of enhancing the process of osteogenesis. 5. Zinc sulphate alone does not appear to exert much influence during fracture healing. 6. Trace element zinc sulphate did not produce any systemic toxic syndrome in the present dose. 7. Multiple banded tetracycline labeling was found to be a suitable method for the study of bone biodynamics. 8. Oxytetracycline used for tetracycline labeling study did not produce any side effect in dose of 30 mg/kg body weight which was much higher to the therapeutic dose.