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  • ThesisItemOpen Access
    Chloral hydrate for general annaesthesia in goats
    (Department of Surgery, College of Veterinary and Animal Sciences,Mannuthy, 1981) Viswanathan, R; KAU; George, P O
    Thirtysix apparently healthy alpins – malabari cross- bred bucks aged from 17 to 30 months and weighing from 22 to 39.5 kg were used for the present study. They were divided into two groups viz., Group I and II, consisting of 18 animals in each. Each of these groups was further divided into three subgroups viz. A, B and C, consisting of six animals in each. Freshly prepared chloral hydrate six per cent solution was administered intravenously at the rate of 1.0, 1.5 and 2.0 ml per kg bodyweight, while triflupromazine hydrochloride (Siquil) at the rate of 0.2 mg per kg bodyweight was also administered intravenously as the premedicant , in group II. Following were the salient results obtained during the present study: When the dose of chloral hydrate was increased, 1) Disappearance of palpebral reflex was quicker and duration was longer, 2) Setting in of incoordination of movements was quicker and the time for assuming the normal gait was longer and 3) Recumbency was seen only in higher doses. Administration of triflupromazine hydrochloride (siquil) as premedicant , increased the efficiency of anaesthetic effect in these animals. Temperature variation consequent on the administration of chloral hydrate, with and without premedication , was not significant the variation being less than 10 P. There was an increase in the rate of respiration and pulse within five minutes of administration of the drug (s), which showed a gradual downward trend. There was reduction in the erythrocyte count, haemoglobin and packed cell volume, while there was slight increase in the leucocyte count. On the basis of the present study, intravenous administration of chloral hydrate, six per cent solution, at the rate of two ml per kg bodyweight, may be recommended in goats, for surgical procedures of about half an hour durations. Premedication with triflupromazine hydrochloride at the rate of 0.2 mg per kg bodyweight would give better results.,
  • ThesisItemOpen Access
    Experimental studies on rumeno-rectal fistula in calves
    (Department of Surgery, College of Veterinary and Animal Sciences, Mannuthy, 1980) Sumangala, M; KAU; Muraleedharan Nair, K N
    Chronic tympany of the rumen is common in cattle. Rumen fistulation has been reported to be successful in the treatment of chronic tympany. Left side external fistulation of rumen has been adopted by many workers. But this was accompanied by seepage of rumen contents and soiling of the flank. While screening the available literature, no reports on an internal rumen fistulation could be found. The effects of rumeno – rectal fistula in experimental calves were studied in the present work. The study was conducted on 12 male calves in two groups , each group consisting of six calves. In the animals of Group – I , laparotomy was performed on the right flank and the right dorsal sac of rumen was anastomosed to the anterior part of the rectum. In the animals of Group II, laparotomy was performed on the left flank and the left dorsal sac of rumen was anastomosed to the anterior part of the rectum. The PH of the rumen contents and the rectal washings, presence of rumen protozoa in the rectal contents, haemoglobin content, packed cell volume, total and differential leucocyte count, nature of dung and the body weight were noted before fistulation and at regular intervals after fistulation. The animals were kept under observation for a period upto 100 days. Closure of the fistula was performed 60 days after fistulation, in two calves, one from each group. The details as described above were noted in these animals also after closure of the fistula. The PH of rectal contents before surgery ranged from 7.3 to 7.5. From the second day after surgery, it ranged between 7.0 and 7.2 in both the groups. The erythrocyte count and haemoglobin content showed a progressive reduction in eight animals and packed cell volume showed a reduction in 10 animals. The variation in the total and differential leukocyte counts were within normal limits. Rumen protozoans were present in the rectal contents from the second day after surgery. Loss of body weight was noticed in all the six animals of Group –I, whereas an increase in body weight was noticed in four animals of Group – II. The feeding habits of the calves were normal. Dung was loose in consistency from the second day after surgery and it contained more fluid soon after drinking water. One animal of Group – I died on the 46th post – operative day, and another one was sacrificed on the 53rd post-operative day. Surgical closure of the fistula was performed in two animals, one from each group. All other animals were sacrificed between 60th and 100th post-operative day. At autopsy omental adhesions were noticed at the site of anastomosis in six calves. The fistula was patent and had a diameter of about 2 cm in 11 animals. Rumen contents were present in the rectum. The site of anastomosis was hard to touch and no other abnormalities could be detected in the rumen and rectum. Complete encapsulation of sutures at the site of anastomosis was noticed in four calves. The healing at the site of anastomosis was complete in all the animals. In the two calves in which closure of the fistula was performed, the healing was uneventful and there was progressive improvement in haemogram values and body weight. It is concluded that functional rumeno – rectal fistula could be established in calves and that it did not cause any untoward clinical manifestations. There was escape of rumen contents through the fistula to the rectum. Surgical closure of the fistula could also be done successfully.
  • ThesisItemOpen Access
    Studies on epidural anaesthesia in goats
    (Department of Surgery, College of Veterinary and Animal Sciences, Mannuthy, 1981) Sarada Amma, T; KAU; George, P B
    The present study was under taken with the object of finding out the effects of epidural administration of varying doses of lidocaine hydrocaine hydrochloride two per cent solution with and without the addition of hyaluronidase in goates. Epidural injection was given at the lumbosacral site using the Brooks’ epidural needle directed perpendicularly downwards. Thirty – six apparently healthy Alpine – Malabari crossbred bucks aged six to fifteen months and weighing seven to twenty – two kilograms were used for the study. The animals were divided into two groups viz., Group 1 and Group 11, each consisting of 18 animals. In Group 1, lidocaine hydrochloride at the rate of 4 mg, 8 mg and 16 mg/kg body – weight was administered as two per cent solution in three Subgroups each consisting of six animals. Similarly in Group 11, lidocaine hydrochloride was administered as two per cent solution along with hyaluronidase (150 I.U./100 ml of lidocaine hydrochloride solution) in three Subgroup each consisting of six animals. Significant positive correlation was noticed between the depth of insertion of the epidural needle and body – weight of the animals. When the dose of lidocaine hydrochloride was increased, there was proportionate decrease in the time of onset and increase in the duration of anaesthesia. In the same dose level when hyaluronidase was added there was further reduction in the time of onset, but the duration of anaesthesia was decreased. On statistical analysis of the data, no significant difference could be seen between 1) the time of onset of flaccidity of tail and relaxation of anal sphincter 2) the duration of flaccidity of tail and relaxation of anal sphincter and 3) the time taken for assuming sternal recumbency and complete relaxation of the muscles of hind – limbs. At a dose of 4 mg/kg body – weight in both the groups, the extent of analgesia was found to be the same, irrespective of addition of hyaluronidase. At higher doses (8 mg and 16 mg/kg body – weight), the extent of analgesia was found to be more. But when hyaluronidase was added, the extent of analgesia was still further increased. ‘Dog sitting posture’ was observed during the onset of anaesthesia only at a dose of 4 mg/kg body – weight. The animals got up only when flaccidity of tail and relaxation of anal sphincter disappeared. At the dose of 4 mg and 8 mg/kg body – weight there were no untoward reactions. But at the dose of 16 mg/kg body – weight lacrimation, salivation, protrusion of tongue, locked jaw, stiffness of head and neck, pedalling movements with the fore – limbs, opisthotonos and dyspnoea were observed in some of the animals during the onset of anaesthesia. Recovery phase was uneventful in all the animals, at all the dose levels. Transient unilateral or bilateral hind – leg lameness, dullness and anorexia were noticed in some of the animals as a post – anaesthetic complication. Epidural injection of lidocaine hydrochloride, two per cent solution at the rate of 4 mg/kg body – weight is recommended for surgical operations of the hind – quarters and inguinal region, while 8 mg/kg body – weight is recommended for operations on the flank region. Hyaluronidase may be added for getting quicker onset and greater extent of analgesia.
  • ThesisItemOpen Access
    Treatment of fracture of tibia in calves and its radiographic evaluation
    (Department of Surgery, College of Veterinary and Animal Sciences, Mannuthy, 1981) Ayyappan, K R; KAU; George, P O
    The present study was conducted on 16 apparently healthy cross – bred bull calves aged from six to nine months and weighing 38 to 75 kg. They were divided into two groups, viz: Group 1 consisting of six animals; and Group 11 consisting of 10 animals. Under chloral nacrosis and epidural anaesthesia, fracture of tibia was created either on the middle or at the lower third after incising the skin medially and sawing the tibia with a wire saw. In Group 1, the skin wound was sutured, fracture reduced and plaster cast applied. Enteromycetin was administered intramuscularly. None of the animals could bear weight on the fractured limb. Wound infection and abscess formation was apparent. Though reduction was proper initially, the fragments showed displacement later. Subsequent radiographs did not show any progressive osteogenic reaction and in none of the animals clinical union was noticed. In Group 11, Kuentscher Cloverleaf nail was directed into the medullary canal with the help of the guide wire and was anchored into the distal fragment. The wound was sutured and plaster of paris cast was applied as an additional support. Excepting two animals, the rest could bear weight by the 10th to 30th day. Streptopenicillin or Munomycin was first administered. This was later followed by a course of Chloramphaenicol after sensitivity test of the pus. Periosteal proliferation was apparent on either fragments by third to fifth week which became more prominent by the fifth to sixth week. Lipping of the fracture edges, obliteration of the fracture line and the formation of the callus were observed by the seventh to eighth week. Later, organisation of the callus took place. Of the ten cases, clinical union had taken place in six animals as evidenced by the dense callus in radiographs. In other cases extension of the local infection into the medullary canal had resulted in non – union of fracture even though osteogenic reaction was in progress inspite of the infection. From the results of the present study it is seen that, (1) Internal fixation using Kuentscher Cloverleaf nail supported by plaster cast and administration of antibiotics would be a satisfactory technique, and (2) reduction followed by immobilisation with plaster cast alone will not be satisfactory in the treatment of tibial fractures in calves.