Browsing by Author "Lalrinkima"

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    Malignant histiocytosis in a dog: A case report
    (2019) Lalrinkima; Thangapandiyan, M; Hemalatha, S; Sudhakar Rao, GV; TANUVAS
    A 3 year old male German Shepherd was presented with a history of swelling on the submandibular region and was brought to Madras Veterinary College, Chennai-600 007 for postmortem examination. Necropsy examination revealed a 10-15 cm white lobulated mass on the right side of subcutis of the submandibular region. Internal examination revealed nodules on cortex of both the kidneys. Severe ulcerative lesions was seen in the stomach and duodenum. Cytologically, discrete round cells pleomorphic, with abundant cytoplasm and ovoid and indented nuclei. Histopathological examination revealed diffuse infiltration of large round to pleomorphic cells with abundant eosinophilic cytoplasm with ovoid to bean shaped nuclei with distinct cell margins. The cells were arranged as loose sheets with minimal fibrous stroma. Nuclei were hyperchromatic with prominent multiple nucleoli. Scanty mitoses was observed. For differential diagnosis of round cell tumors mast cells were ruled out by toludine blue staining which was found to be negative. Immunohistochemistry for mast cell tumor was carried out for Ckit and was found to be negative. Specific expression of immunohistochemical markers for histiocytic cell type CD 18 showed diffuse intense cytoplasmic positivity for the markers. Both dermal and metastatic areas in the kidney expressed these specific histiocytic markers.
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    A pathological study on brain of dogs at necropsy
    (2020-02) Lalrinkima; Hemalatha, S; TANUVAS
    A pathological study on canine brain tissue was carried out on necropsy cases received at the Department of Veterinary Pathology Madras Veterinary College, Chennai –600 007 during March to July 2019. Twenty seven dogs presented for necropsy were considered for the study. The clinical history, age, breed and sex wise distribution were recorded. Gross changesif any was observed and samples of brain tissues were collected for histopathological studies. Brain impression smears were stained with William’s modification of van Gieson’s stain and observed for presence of negri bodies. Out of 27 dogs examined eight cases showed presence of negri bodies No significant gross changes were observable except for congestion, oedema and haemorrhages. Histopathological studies revealed non suppurative meningoencephalitis and presence of stray intranuclear inclusions in glial cells of cerebellum with demyelination ina dog with clinical history of canine distemper. Brain tissuesof dogs with clinical diagnosis of rabies showed subdural haemorrhages, marked gliosis, perivascular lymphocytic cuffing, neurophilic vacuolation and presence of intracytoplasmic eosinophilic inclusions in neurons of cerebral grey matter. Based on our study we report that lesions in brain of canine are uncommon and was often recorded in viral infections of canine.
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    A Serological Study on Porcine Parvovirus among Pigs in Chennai, Tamil Nadu
    (Haryana Vet., 2022-06) Lalrinkima; Hemalatha, S.; Nagarajan, K.; Raj, G. Dhinakar; Thangavelu, A.; Rao, G.V. Sudhakar; Balasubramanyam, D.; TANUVAS