Please use this identifier to cite or link to this item: http://krishikosh.egranth.ac.in/handle/1/95247
Authors: ANITA MEENA
Advisor: Dr. (Mrs.) Nalini Kataria
Title: INTERRELATION OF ALDOSTERONE WITH OXIDATIVE STRESS AND ELECTROLYTES IN RATHI COWS DURING HOT AMBIENCE
Publisher: Rajasthan University of Veterinary and Animal Sciences, Bikaner - 334001
Language: en
Type: Thesis
Agrotags: weeds, pigeonpeas, control methods, herbicides, yields, planting, harvesting, research methods, land resources, grain
Abstract: The present investigation was carried out in apparently healthy Rathi cows, between 4 and 10 years of age, to determine interrelation of aldosterone with oxidative stress and electrolytes in the serum during moderate and extreme hot ambiences. Moderate ambience comprised of October-November and hot ambience of May and June. Animals were broadly divided according to physiological states i.e. pregnant and non-pregnant and primipara and multipara. To evaluate interrelation of aldosterone with oxidative stress and electrolytes during hot ambience, the results of various parameters analysed were compared with those analysed during moderate months serving as control.The serum parameters determined included hormone aldosterone, oxidative stress markers viz. super oxide dismutase (SOD), glutathione reductase (GR), catalase (CAT), peroxidase (PO) and gamma glutamyl transferase (GGT) and electrolytes viz. sodium, potassium, chloride, calcium, phosphorus and magnesium. The moderate mean values of serum aldosterone; superoxide dismutase; glutathione reductase; catalase; peroxidase; gamma glutamyl transferase; sodium, potassium; chloride; calcium; inorganic phosphorus and magnesium were 0.25±0.0009 n mol L-1; 179.00±1.28 kUL-1; 9.00±0.09 kUL-1 ; 74.25±1.56 kUL-1 ; 57.50±1.00 mUL-1 ; 45.50±1.52 UL-1 ; 133.50±0.52 m mol L-1 ; 5.65±0.001 m mol L-1 ; 109.50±0.32 m mol L-1 ; 2.81±0.001 m mol L-1 ; 1.83±0.001 m mol L-1 and 0.92±0.001 m mol L-1 , respectively. The mean values of serum aldosterone, SOD, GR, CAT, PO, GGT, sodium and chloride were significantly (p≤0.05) higher during hot ambience in comparison to moderate ambience, respectively. In each ambience, the mean value of each parameter in non pregnant animals was lower than in pregnant animals and was significantly (p≤0.05) higher in multipara animals than primipara. The highly significant (p≤0.01) effects were also revealed by analysis of variance for each case. The mean values of serum potassium, calcium, phosphorus and magnesium showed the reverse trend. They were significantly (p≤0.05) lower during hot ambience in comparison to moderate mean value, respectively. In each ambience, the mean value of each parameter in non pregnant animals was higher than in pregnant animals and was significantly (p≤0.05) lower in multipara animals than primipara in each ambience, respectively. The highly significant (p≤0.01) effects were also revealed by analysis of variance for each case. The interactions between ambience X group A (non pregnant and pregnant ); and ambience X group B (primipara and multipara) and between group A X group B were studied for each parameter and were observed to be highly significant (p≤0.01) for each case. Interrelation of aldosterone with oxidative stress and electrolytes in Rathi cows during hot ambience were observed.Maximum percent variation (268.68) due to hot ambience was observed in the mean value of GGT, which increased significantly (p≤0.05) in comparison to moderate mean value. Minimum variation was observed in the potassium (-6.19) levels, which decreased significantly (p≤0.05) in comparison to moderate mean value. When percent variations of the various parameters were compared between pregnant and non-pregnant animals and between primipara and multipara cows, it was observed that extent of percent variation for each parameter was greater in pregnant cows in comparison to non-pregnant cows and in multipara cows in comparison to primipara cows. All the correlations were highly significant (p≤0.01) except of SOD & Ca; SOD & P; SOD & Mg; GR & Mg; CAT & Mg; PO & K; PO & Mg; GGT & Mg; Na & Ca; Na & Mg; K & P; K & Mg; Cl &P; Cl &Mg; Ca &Mg and P &Mg, which were significant (p≤0.05). All the correlations were positive except of ALD & K; ALD &Ca; ALD &P; ALD &Mg; SOD &K; SOD &Ca; SOD &P; SOD & Mg; GR &K; GR &Ca; GR &P; GR &Mg; CAT & K; CAT &Ca; CAT &P; CAT &Mg; PO& K; PO& Ca; PO&P; PO&Mg; GGT&K; GGT&Ca; GGT&P; GGT&Mg;Na&K; Na&Ca; Na&P and Na&Mg, which were negative. The present research work has assessed the interrelation of aldosterone with the oxidative stress as well as with electrolytes. It can be concluded that extreme hot ambience produced the oxidative stress in the Rathi cows of all physiological states. An interrelation was observed among aldosterone, oxidative stress markers and electrolytes. The extent of development of oxidative stress was observed to be higher in pregnant animals in comparison to non-pregnant and in multipara animals in comparison to primipara animals. It indicated the presence of oxidative stress in the form of values which can be useful to redefine the role of oxidative stress in physiological variations and extreme environmental conditions and can be used for clinical diagnosis and in health management of these animals. The results of present study will provide baseline work for future research in the Rathi animals in the field of veterinary clinical physiology.
Subject: Animal Physiology
Issue Date: 2014
Appears in Collections:Thesis

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