Please use this identifier to cite or link to this item: http://krishikosh.egranth.ac.in/handle/1/5810086156
Authors: JUPAKA SHASHANK
Advisor: Dr. S. AYODHYA
Title: STUDY ON CERTAIN ASPECTS OF GASTROINTESTINAL NEMATODIASIS IN GOATS AND THEIR THERAPEUTIC MANAGEMENT
Publisher: PVNR TVU
Language: en
Type: Thesis
Agrotags: null
Abstract: The present investigation was carried out to study the incidence, egg per gram (EPG), hemato-biochemical findings and therapeutic efficacy of certain therapeutic drugs in treatment of gastrointestinal nematodal parasitic infestation in goats. 368 goats that were presented to the Campus Veterinary Hospital and Ambulatory Clinical Services, Mylardevpally, College of Veterinary Science, Rajendranagar, Hyderabad, from December-2017 to June-2018 were randomly selected and screened for gastrointestinal nematodal infestation by different techniques (gross, direct faecal smear, sedimentation and flotation) Out of which 140 goats (38.04%) were found positive for gastrointestinal nematodal infestation. Ten apparently healthy goats (Group I) which were negative for gastrointestinal nematodal infestation were selected, subjected to haematological and biochemical investigations and they served as healthy control group. Goats positive for gastrointestinal nematodal infestation were randomly divided into two groups (II and III) with each group having 10 positive cases. Among 140 positive cases 64 were in the age group of 0 month to 1 year with an incidence of 45.71% followed by 39 (36.79%) in 1 to 2 years, 24 (34.29%) in 2 to 4 years and least in 13 (25%) goats which were more than 4 years of age. The incidence was more in males (75) than females (65). Out of 140 goats, the incidence of Strongyles spp., Trichuris spp., and Strongyloides spp., was 88 (62.86%), 33 (23.57%) and 19 (13.57%), respectively. Strongyles spp. was the most common infestation in goats followed by Trichuris spp. and Strongyloides spp. Single nematodal parasitic infestation had highest rate of 85% (119 samples) whereas 15% (21 samples) had mixed nematodal parasitic infestation. Among 119 with single nematodal infestation, 72 (60.50 %) Strongyles spp., 27 (22.69 %) Trichuris spp. and 20 (16.81%) Strongyloides spp., Among 21 mixed nematodal parasitic infestaions, Strongyles spp. + Trichuris spp. in 13 (61.90%) goats and Strongyles Spp. + Strongyloides spp. in 08 (38.10%) goats. Significant (p<0.05) decrease in mean values of haemoglobin (9.73 ± 0.01 and 9.67 ± 0.01 g %), PCV (26.59 ± 0.58 and 26.21 ± 0.33 %), TEC (11.34 ± 0.01 and 11.23 ± 0.007 x 106 μL) and lymphocytes (49.14 ± 0.95 and 49.42 ± 0.34 %) in goats of group II and III, respectively, whereas significant p<0.05) increase in TLC (11.09 ± 0.02 and 10.98 ± 0.02 x 103 μL), eosinophils (7.12 ± 0.17 and 6.97 ± 0.10 %) and monocytes (3.01 ± 0.03 and 2.96 ± 0.01%), respectively. Post treatment, analysis of blood on day 7 revealed significant (p<0.05) increase in mean values of haemoglobin (11.10 ± 0.01 and 10.84 ± 0.01 g %), PCV (35.47+0.14 and 33.5 ± 0.45%), TEC (13.51 ± 0.01 and 12.93 ± 0.01 x 106 μL) and lymphocytes (53.45 ± 0.67 and 53.46 ± 0.28 %) in goats of group II and III, respectively, whereas significant decrease in TLC (10.79 ± 0.004 and 10.87 ± 0.003 x 103 μL), eosinophils (3.95 ± 0.15 and 3.98 ± 0.13 %) and monocytes (2.68 ± 0.01 and 2.65 ± 0.01 %), respectively. Significant (p<0.05) decrease in the values of TSP (5.14 ± 0.03 and 5.31 ± 0.03 g/dl), albumin (1.92 ± 0.04 and 2.02 ± 0.04 g/dl) in goats of group II and III, respectively, whereas, significant (p<0.05) increase in globulin (3.22± 0.03 and 3.29 ± 0.05 g/dl) in goats of group II and III, respectively when compared with the healthy group on day 0. Significant increase (p<0.05) in the values of TSP (6.45 ± 0.07 and 6.42 ± 0.06 g/dl), albumin (3.81 ± 0.01 and 3.84 ± 0.03 g/dl) in goats of group II and III, respectively, whereas significant (p<0.05) decrease in globulin (2.64 ± 0.07 and 2.58 ± 0.04 g/dl), respectively on day 7 post treatment. Significant (p<0.05) increase in Alanine Aminotransferase (ALT/SGPT) values in group II, and III (26.09 ± 0.33 and 24.19 ± 0.52 U/L), respectively and significant decrease in group II, and III (17.08 ± 0.12 and 18.07 ± 0.28 U/L), respectively on day 7 post treatment. Group II goats treated with ivermectin 200 μg/kg b.wt S/C, decreased (p<0.05) Eggs per gram count. i.e., 220 ± 38.87, 0 ± 0 and 0 ± 0, on 3, 5 and 7th day, respectively. Group III goats treated with levamisole 7.5 mg/kg b. wt P/O on day 0, Eggs per gram count decreased (p<0.05) on day 3, 5 and 7. i.e., 320 ± 59.25, 50 ± 30.73 and 0 ± 0, respectively.
Subject: Veterinary Medicine
Theme: VMD
These Type: M.V.Sc.
Issue Date: 2018-12-03
Appears in Collections:Thesis

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