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Authors: Joju Johns
Advisor: George Chandy
Publisher: Kerala Veterinary and animal science university, Pookode
Language: en
Type: Thesis
Pages: 114
Agrotags: null
Keywords: Chemical immobilisation, Anaesthetic drugs, Ungulate anaesthesia
Abstract: The efficacy of xylazine-ketamine anaestesia with and without oral Haloperidol premedication was evaluated in 20 captive Spotted Deer stags undergoing routine vasectomy and randomly allocated in to two groups of ten each. Group I animals were anaesthetised with a combination of xylazine and ketamine at the rate of 3 and 2 mg/kg b.wt. by darting. Group II animals were orally premedicated with haloperidol at the rate of 1 mg/kg b.wt. Six hours prior to xylazine-ketamine anaestesia as in group I. Yohimbine was administered at the rate of 0.3 mg/kg b.wt. divided equally and administered IV and IM following surgery and translocation which lasted for an average of 35 minutes. Group II animals were calmer and easier to dart, showing better quality of induction of anaesthesia with shorter induction time. Group I animals showed better quality of recovery with a shorter recovery time. Rectal temperature, heart rate, serum cortisol and plasma lactate were lower in Group II animals, indicating reduced stress and physical exertion. Animals of both groups were hypoxemic throughout the study and PCO2 increased with time in both groups. Blood pH was found to be acidic in both groups with significantly lower pH observed in Group I immediately after induction. Creatine kinase and blood glucose were elevated in both groups during the procedure but did not differ significantly between groups. Thirty percent of animals of each group showed ruminal tympany. Ventricular premature contraction and second- degree atrio ventricular block were seen in one animal of Group I and Group II respectively. Haemetological parameters were within the reference ranges in all animals. Overall, haloperidol premedication was observed to have several benefits in xylazine-ketamine anaestesia in Spotted deer and was not associated with any additional complication. However, quality of anaesthesia may be improved by reducing the dose of xylazine in haloperidol premedicated animals.
Subject: Veterinary Surgery and Radiology
Theme: Haloperidol premedication
These Type: M.V.Sc.
Issue Date: 2014-07-14
Appears in Collections:Thesis

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