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Authors: Praveen Kumar
Advisor: Jain, V. K.
Title: Etiological, Haemato-biochemical and Therapeutic Studies on Respiratory Disease in Buffaloes
Publisher: LUVAS
Language: en
Type: Thesis
Keywords: Bovine respiratory disease; Haemato-biochemical; Culture examination, Antibiotic sensitivity, Kanamycin; Enrofloxacin; Moxifloxacin; Cefoperazone; Buffaloes
Abstract: Bovine respiratory disease is a multi-factorial disease involving infectious agents, compromised host immune system and environmental factors and represents a major economic and health problem in bovine population worldwide. The present study included 37 clinical cases of buffaloes affected with respiratory disease brought to VCC, LUVAS, Hisar with the complaint of anorexia, fever, nasal discharge, coughing, dyspnoea and abnormal lung sounds on auscultation of thoracic area. The diagnosis of bovine respiratory disease was based on the culture of nasal swabs, classical clinical signs of the disease, culture sensitivity testing, haemato-biochemical profile and radiological examination. Out of these, 28 animals divided in four groups (I,II,III and IV) consisting of seven animals in each group and were treated with (I) kanamycin @ 6-7.5 mg/kg b.wt. b.i.d., (II) enrofloxacin @ 5 mg/kg b.wt. s.i.d., (III) moxifloxacin @ 5 mg/kg b.wt. s.i.d. and (IV) cefoperazone @ 20 mg/kg b.wt. in divided doses I/M along with supporative therapy. Haemato-biochemical studies revealed appreciable leukocytosis, neutrophilia, hyperproteinemia, hyperglobulinemia, hyperglycemia, increased hepatic enzyme activity level, compromised kidney function, while low A/G ratio, hypoalbuminemia, hyponatremia, hypochloremia and reduced anion gap in affected animals. Various bacteria isolated from nasal swab samples were Staphylococci (23), Streptococci (11), E. coli (7), Klebsiellla (6), E. coli (5), Psedomonas (1) and 37.83% animals were having mixed infection. Maximum sensitivity shown towards chloromphenicol (75%), co-trimoxazole (75%), ofloxacin (72.22%) while least towards ampicillin plus cloxacillin (5.56%), ceftriaxone plus tazobactum (16.67%), clindamycin (16.67%), amoxyclav (19.44%), kanamycin (30.55%), moxifloxacin (35.55%) and tetracycline (38.88%) in vitro. Out of four antibiotics used in the therapeutic trial, enrofloxacin was found to be most effective antimicrobial drug as compared to kanamycin, moxifloxacin and cefoperazone in the therapeutic management of clinical cases on the basis of remission of clinical symptoms.
Subject: Veterinary Medicine
Theme: Etiological, Haemato-biochemical and Therapeutic Studies on Respiratory Disease in Buffaloes
These Type: M.V.Sc.
Issue Date: 2017
Appears in Collections:Thesis

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