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Authors: Dongaonkar, K. R.
Advisor: Gulavane, S. U.
Title: Clinical Studies On Effect Of Laparoscopic Ovariectomy Along With Intra-Gestational Sac Injection Of Postassium Chloride In Pregnant Bitches
Publisher: MAFSU, Nagpur.
Language: en
Type: Thesis
Pages: 112
Agrotags: null
Keywords: Laparoscopic, Ovariectomy, Intra-Gestational, Sac, Injection, Postassium, Chloride, Pregnant Bitches
Abstract: Laparoscopic Ovariectomy was performed and intra-gestational sac injections of Potassium chloride were administered at the dose of 1 mEq/sac in eight; 40 to 50 days pregnant bitches (Group A) without any untoward complications and which resulted in abortion and complete uterine evacuation within 45.00 ± 20.03 hours (24-84 hours). Electrocardiographic monitoring post-KCl injections suggested that there was no evidence of maternal-side hyper-kalemic complications. On ultrasonography, time of initial detection of foetal death was 18.85 ± 6.41 hours (12- 24 hours) post-laparoscopic ovariectomy and intra-sac Potassium chloride. Mean interval between initial detection of foetal death and documentation of complete uterine evacuation was 29.14 ± 19.42 hours (12-60 hours). Foetal heart rates recorded over several ultrasound scans of all the bitches, ranged from 191 to 279 beats per minute and there was no evidence of foetal distress during induced abortion. Post-abortion uterus after complete evacuation of conceptuses, on sonography, was observed to have minimal intra-luminal fluid and was similar in appearance to a post-partum uterus. Viscous brown vulvar discharge preceded foetal expulsion in all bitches by about 12 hours and all the expelled foetuses were found to be dead on observation. Interval between laparoscopic ovariectomy along with intra-sac Potassium chloride and expulsion of first foetus, ranged between 12 to 48 hours post-surgery. Haematological and biochemical profiling for each bitch revealed that there was statistically significant rise in pre and post-operative values of haemoglobin, total erythrocyte count, plasma cell volume and total leukocyte count. However, all the bitches aborted without any clinically significant complications and convalesced back to fitness speedily and had no post-operative complications. Laparoscopic Oophorectomy resulted in a sharp fall in serum progesterone concentrations from 11.62 ± 2.63 ng/ml (06.46 to 14.11 ng/ml) on day of surgery to 1.31 ± 0.47 ng/ml (0.92 to 2.14 ng/ml) 24 hours thereafter, which was statistically significant and to 0.540 ± 0.240 ng/ml (0.23 to 0.84 ng/ml) and 0.338 ± 0.222 ng/ml (0.12 to 0.74 ng/ml) on day 3 an 7 post surgery, respectively. In control/ Group B bitches mean serum progesterone was 14.96 ± 12.01 ng/ml and 9.77 ± 06.54 ng/ml on day 0 and 7 respectively. No significant difference was observed between mean serum progesterone of day 0 and 7 in Group B. It was concluded that Laparoscopic ovariectomy is technically feasible and safe procedure for neutering 40-50 day pregnant bitches and results in successful uterine evacuation.
Subject: Veterinary Pharmacology
Theme: Clinical Studies On Effect Of Laparoscopic Ovariectomy Along With Intra-Gestational Sac Injection Of Postassium Chloride In Pregnant Bitches
These Type: M.V.Sc.
Issue Date: 2011
Appears in Collections:Thesis

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