Please use this identifier to cite or link to this item: http://krishikosh.egranth.ac.in/handle/1/5810027163
Authors: Summaya Gulzar
Advisor: Khurana, Rajesh
Title: Evaluation of thyroid hormones and their significance in canine dermatitis
Publisher: LUVAS
Language: en
Type: Thesis
Keywords: AKP, Canines, Cholesterol, Hypothyroidism, T3, T4, Triglycerides, TSH.
Abstract: The present study was taken under with the objective to study the prevalence of hypothyroidism in Hisar and other adjoining areas. The study was carried out for a period of seven months from September 2010 to March 2011 at Teaching Veterinary Clinical Complex (TVCC), Lala Lajpat Rai University of Veterinary and Animal Sciences, Hisar. During this period, a total of 1728 dogs were screened for the symptoms of hypothyroidism. Out of them, 325 dogs were having various dermatological problems. A total of 50 dogs were suspected to be suffering from hypothyroidism on the basis of history, presence of typical lesions/symptoms, behavior and clinical examination. In addition, 10 dogs were suspected of having hypothyroidism at Private Pet Clinics of Faridabad and Gurgaon. Blood samples were taken from five apparently healthy dogs that served as the control group. Blood was collected from cephalic/saphanous vein under aseptic conditions. Serum was collected and stored in clean and dry plastic vials with cap. After collection, samples were maintained at a temperature of -20˚C until analyzed for the estimation of tri-iodothyronine (T3), thyroxine (T4), thyroid stimulating hormone (TSH), cholesterol, triglycerides and alkaline phosphatase. The estimation of T3, T4 and TSH was done by Electrochemiluminescence Immunoassay (ECLIA) technique using COBAS-E immunoassay analyzer. The estimation of cholesterol, triglycerides, AKP estimation was carried out by employing auto analyzing kit AUTOPAK in autoanalyzer. The results showed that the prevalence of hypothyroidism in Hisar and other adjoining areas is 0.4 per cent. Hypothyroidism was mostly prevalent in dogs of Labrador breed, adult dogs of age 4 years or more and those with body weight 40 kilograms or above. The levels of T3 and T4 hormones were found less in dogs with dermatological disorders in comparison to the healthy control. The mean cholesterol levels in dogs with various dermatological affections were found to be greater than the normal values. There was a positive correlation of TSH with cholesterol and negative correlation between T3, T4 with cholesterol in dogs with dermatitis.
Subject: Preventive Veterinary Medicine and Epidemiology
Theme: Evaluation of thyroid hormones and their significance in canine dermatitis
These Type: M.V.Sc.
Issue Date: 2011
Appears in Collections:Thesis

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