Please use this identifier to cite or link to this item: http://krishikosh.egranth.ac.in/handle/1/5810006466
Authors: PATEL, AMRATA
Advisor: Shukla, Dr. P.C.
Title: HAEMOPROTOZOAN INFECTION IN GOATS WITH SPECIAL REFERENCE TO THERAPEUTIC MANAGEMENT OF CAPRINE BABESIOSIS
Publisher: Nanaji Deshmukh Veterinary Science University, Jabalpur (M.P.)
Language: en
Type: Thesis
Pages: 53
Keywords: caprine haemoprotozoan,creatinine
Abstract: In India, caprine haemoprotozoan infection is common due to favourable climate for growth of parasites and their vectors. It causes economic losses particularly in tropical and subtropical countries. The present work in goats was aimed to study the prevalence of caprine haemoprotozoan infection in and around Jabalpur City, to study the various clinical and haemato-biochemical alterations in caprine babesiosis and to evaluate the therapeutic efficacy of drugs against caprine babesiosis. A total of 800 blood samples of goats were collected from Amanala goat unit, Livestock farm, Adhartal, goats brought to TVCC, Jabalpur, Government Veterinary Hospital, Omti, private clinics and areas in and around Jabalpur city from August 2012 to May 2013. Confirmation of haemoprotozoan was done by microscopic examination of the stained blood smears. For prevalence study apart from various clinical signs age, sex and breeds of all the goats positive for babesiosis were also recorded. For haematological and biochemical estimations 5 ml blood was collected aseptically on day 0 (pre-treatment) and day 15 and 30’ (post-treatment) from the three treatment groups as well as control group. To study the efficacy of drugs against caprine babesiosis, 18 goats positive for Babesia organism were taken and divided into 3 groups (T1,T2 and T3) having 6 goats in each group. Besides these a group of 6 healthy goats was kept as control group. Group T1 was administered with inj. Oxytetracycline LA @ 20 mg/kg b.wt, I/M, 2 doses at 96 hrs intervals, group T2 was administered with inj. Diminazene aceturate @ 3.5 mg/kg b.wt., I/M, 2 doses at 24 hrs intervals while in group T3 inj. Buparvaquone @ 2.5 mg/kg b.wt., I/M, 2 doses at 96 hrs intervals was administered. The overall prevalence of caprine haemoprotozoan, Babesia and Theileria was reported to be 3.9%, 3.5% and 0.4% respectively. Among caprine haemoprotozoan infection and Babesia the higher prevalence was found in age group >3 years of age i.e. 5.71% in age group >5 years of age and 4.21% in age group 3 to 5 years and minimum in age group <1 year of age i.e. 1.71%. The goats affected with Theileria were between 1 to 3 years of age thus the prevalence of Theileria in age group 1-3 years of age was 1.33% i.e. 3 out of 225 goats. The sex wise prevalence study revealed prevalence of caprine haemoprotozoan infection in males and females was 3.37% and 4.51% respectively. The sex wise prevalence of Babesia in males and females goats was 2.92% and 4.23% respectively. Prevalence of Theileria in males and females goats was 0.45% and 0.28% respectively. Breed wise prevalence of caprine haemoprotozoan infection was noticed higher in well defined breeds (Sirohi, Barbari and Jamunapari) i.e. 5.34% followed by non-descript goats i.e. 1.36%. Among Babesia infection the maximum breed wise prevalence was noticed in well defined breeds (Sirohi, Barbari and Jamunapari) i.e. 4.75% followed by non-descript goats i.e. 1.36%. In Thelieria infection the breed wise prevalence was noticed in only on well defined breeds (Sirohi, Barbari and Jamunapari) i.e. 0.59%. Clinical signs in goats affected with Babesia were pale mucous membranes (85.7%), loss of appetite (75%), nasal discharge (35.7%) and coughing (32.1%), followed by diarrhoea (60.1%), emaciation (53.4%) and haemoglobinuria (7.1%) along with presence of ticks on body in 82.1% caprine. Among the various clinical parameters temperature, pulse rate and respiration rate increased significantly (P≤0.01) with that of healthy control group on the day 0 pre treatment. Among the various haematological parameters total erythrocyte count (millions/µl), haemoglobin concentration (g/dl), packed cell volume (%) and neutrophil (%) was significantly decreased (p≤0.01) while, total leukocyte count (thousands/µl) and lymphocyte (%) were significantly increased (p≤0.01) than healthy control group on day 0 pre treatment. However, non-significant changes occurred in monocyte (%) and eosinophil (%) between healthy and affected goats on the day 0 pre treatment. The results of biochemical parameters showed that a statistically significant increase (p≤0.01) occurred in alanine amino transferase (U/l), aspartate amino transferase (U/l), alkaline phosphatase (U/l), blood urea nitrogen (mg/dl), creatinine (mg/dl) and total bilirubin (mg/dl) while, significant decrease (p≤0.01) was noticed in total plasma protein (g/dl) and blood glucose (mg/dl) in affected goats as compared with healthy goats. The results showed that group T2 was superior to groups T1 and T3 as all the 6 goats (100%) were recovered on day 15 post treatment, as compared to group T1 and T3 i.e. 5 out of 6 (83.33%) and 1 out of 6 (16.67%) goats respectively.
Description: graph
Subject: Veterinary Medicine
Theme: scientific research
Research Problem: HAEMOPROTOZOAN INFECTION IN GOATS WITH SPECIAL REFERENCE TO THERAPEUTIC MANAGEMENT OF CAPRINE BABESIOSIS
These Type: M.SC
Issue Date: 2013
Appears in Collections:Thesis

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